Monday, December 22, 2008

Drug-induced cholestasis

Drugs that can cause cholestatic jaundice:
Chlorpromazine
Antibiotics (flucloxacillin, fusidic acid, co-amoxiclav, nitrofurantoin)
Prochlorperazine
Sulfonylureas
Anabolic steroids
Gold
Oral contraceptives

If you're gonna get jaundice, get it from eating CAP SAGO!

Source: Oxford Handbook of Clinical Medicine

Learning prompted by one of my patients developing jaundice post-op. LFT showed cholestatic picture too! Remitted spontaneously after stopping IV Augmentin (after checking OHCM!).

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