Monday, December 22, 2008

Rye classification for Hodgkin's lymphoma

The Rye classification for Hodgkin's lymphoma, in order of frequency
Nodular Sclerosis
Mixed cellularity
• lymphocyte Depleted
• lymphocyte Predominant

Lymphocyte-predominant has the best prognosis while lymphocyte-depleted has the worst.

A comparison can be found in Blood: Principles and Practice of Hematology online

Naked Spiders Make Dogs Puke... don't ask me why!

Drug-induced cholestasis

Drugs that can cause cholestatic jaundice:
Chlorpromazine
Antibiotics (flucloxacillin, fusidic acid, co-amoxiclav, nitrofurantoin)
Prochlorperazine
Sulfonylureas
Anabolic steroids
Gold
Oral contraceptives

If you're gonna get jaundice, get it from eating CAP SAGO!

Source: Oxford Handbook of Clinical Medicine

Learning prompted by one of my patients developing jaundice post-op. LFT showed cholestatic picture too! Remitted spontaneously after stopping IV Augmentin (after checking OHCM!).

Antibiotic-induced fever



Six antibiotics known to cause fever are:
⟐ Procainamide
⟐ Quinidine
⟐ Penicillin
⟐ Isoniazid
⟐ Nitrofurantoin
⟐ Erythromycin


Antibiotic-induced fevers are a thorny issue, together they spell PorQPINE!

Source: Family Practice Notebook.com